HSV1 Pulls the Deamidation tRIGger

Plant Signaling: Ubiquitin Pulls the Trigger on Chloroplast Degradation

Diverse proteolytic pathways regulate chloroplasts. Recent work has revealed significant new roles for chloroplast ubiquitination in stress adaptation, involving targeted protein removal through the ubiquitin-proteasome system, or selective, whole-chloroplast degradation.

What Pulls the Trigger of Reflection? — Conflict Awareness and Adaptive Scaffolding —

Reflections on a sticky situation: how surface contact pulls the trigger for bacterial adhesion.

Adhesion of bacterial cells to surfaces can be mediated by a wide variety of extracellular structures, which can either recognize specific molecular motifs or adhere in non-specific ways to multiple types of surfaces. The attachment is thought to be highly regulated, but the underlying sensory mechanism(s) are poorly understood. In the α-proteobacterium Caulobacter crescentus, the formation of ...

Protein translocation pulls the plug

Protein translocation pulls the plug embrane-bound compartments present an immediate problem: proteins need to get into and across those membranes. Now, we have the first picture of how that process works, thanks to the structure determined and colleagues. They find that a single SecY complex from Methanococcus jannaschii forms an hourglass-shaped pore with a basal plug that probably swings out...

Commentary: Smoke pulls the blinds.

In this issue, Pokhrel et al. publish an intriguing study from the Nepal–India border region that calls our attention to both what it shows and what it hides.1 This case–control study suggests an almost 2-fold risk for cataract related blindness among women using solid fuel unvented stoves. This risk gradient is similar to the one described between smokers and non-smokers.2,3 As in many economi...